Confused about ESPN+, ESPN Plus and ESPN Regional?

The Wiki page does a good job of explaining this!

There are also going to be some changes coming August 2007, when the Big Ten Network comes alive. The Big Ten network is a collaboration between the Big 10 and Fox Sports, so it will affect some of the games carried by ESPN+ and ESPN Pay Per View, Game Plan and Full Court. Direct TV picked it up already. Fox Sports could easily make this channel available in August 2007 by switching one of its three Fox College Sports to be the Big Ten Network channel part-time or full-time.

This continues the trend of C-USA and CSTV, along with "the mtn", the collaboration between CSTV, the Mountain West and Versus (formerly OLN, owned by Comcast).